Parkinson’s disease: hold the AMPs
Pathologist Keqiang Ye and colleagues recently published a paper in PNAS that may have implications for Parkinson’s disease pathology and treatment strategies. The protein alpha-synuclein is a bad...
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More pieces in Parkinson’s puzzle: VMAT2 and SV2C
The drug target VMAT2 has appeared in biomedical news lately because of a pair of FDA approvals. One medicine treats the iatrogenic movement disorder tardive dyskinesia, the first approved to do so,...
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Drug discovery: Alzheimer’s and Parkinson’s spurred by same enzyme
Alzheimer’s disease and Parkinson’s disease are not the same. They affect different regions of the brain and have distinct genetic and environmental risk factors. But at the biochemical level, these...
View ArticleEmory neuro-researchers in Alzforum
Just a shoutout regarding Emory folks in Alzforum, the research news site focusing on Alzheimer’s and other neurodegenerative disorders. Alzforum recently highlighted proteomics wizard Nick Seyfried’s...
View ArticleTug of war between Parkinson’s protein and growth factors
Alpha-synuclein, a sticky and sometimes toxic protein involved in Parkinson’s disease (PD), blocks signals from an important brain growth factor, researchers have discovered. The results were published...
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Inflammation in PD hits the gut
Several groups studying Parkinson’s have had a hunch – a gut feeling, even – that intestinal inflammation is involved in driving the disease. Now Emory researchers led by Malu Tansey, PhD have some...
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The blue spot: where seeds of destruction begin
Neuroscientist and geneticist David Weinshenker makes a case that the locus coeruleus (LC), a small region of the brainstem and part of the pons, is among the earliest regions to show signs of...
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Neurodegeneration accelerated by intestinal bacteria?
An influential theory about the anatomical trajectory of Parkinson’s disease is getting a microbial boost. The idea, first proposed by neuroanatomist Heiko Braak in 2003, is that pathology and...
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The earliest spot for Alzheimer’s blues
The Emory laboratories of Keqiang Ye and David Weinshenker recently published a paper on ApoE, the most common genetic risk factor for late-onset Alzheimer’s. The findings, published in Acta...
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Insights into Parkinson’s balance problems
Loss of balance and falls are big concerns for people living with Parkinson’s disease and their caregivers. Researchers at Emory and Georgia Tech recently published a paper in PLOS ONE providing...
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